What Men Need to Know About Anastrozole’s Side Effects

Anastrozole is primarily used to treat breast cancer in postmenopausal women by inhibiting aromatase, reducing estrogen levels. In men, it’s used off-label for gynecomastia or high estrogen due to steroids, but can cause side effects like joint pain, hot flashes, and fatigue. Reduced estrogen from long-term use may decrease bone density, raising osteoporosis risk. Mood changes and cholesterol effects can impact cardiovascular health, so careful medical monitoring is essential to balance treatment benefits and risks.

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