IGF-1-BP3: Potential Implications for Growth and Metabolism

IGF-1-BP3, a key regulatory protein, modulates insulin-like growth factors (IGFs) activity, especially IGF-1. It is the most abundant IGF-binding protein in human serum, crucial for growth and development by extending IGFs’ half-life and modulating their receptor interaction. IGF-1-BP3 affects cellular processes like proliferation and differentiation, and its levels are studied in clinical settings for growth and metabolic disorders. In cancer, it may influence tumor growth, underlining its significance in both normal physiology and pathological conditions.

IGF-1-BP3

IGF-1-BP3, or Insulin-like Growth Factor 1 Binding Protein 3, is integral in regulating IGF-1, a growth factor crucial for cell development. It binds with IGF-1 to modulate its interaction with receptors, enhancing physiological processes and promoting health benefits such as better skin elasticity, muscle growth, and metabolism.

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