Chloromethylandrostenediol: Revolutionizing Steroid
Although CMA was sold as a “prohormone” or “prosteroid” of chloromethyltestosterone (CMT; also known more commonly as methylclostebol), it is likely that the conversion is far from complete and that much of the activity of the drug may be attributable to its unchanged form. Due to the presence of a chloro group at the C4 position, CMA cannot be aromatized, and for this reason, poses no risk of estrogenic side effects like gynecomastia at any dosage. It is not extensively metabolized by 5α-reductase and exhibits relatively greater anabolic than androgenic activity, but is still capable of producing androgenic side effects like oily skin, acne, and increased growth of facial and body hair, as well as virilization in women. As with other 17α-alkylated AAS, CMA may pose a risk of hepatotoxicity.
