Cytadren: And the Role of a Suppressant in Endocrine Therapy

Cytadren, or aminoglutethimide, is used primarily for managing Cushing’s syndrome and certain hormone-sensitive cancers like breast cancer. It works by inhibiting the enzyme aromatase, reducing hormone production, which can help in slowing tumor growth. Caution is advised due to potential side effects such as dizziness, drowsiness, and skin rash. Its use is typically monitored closely and considered when other treatments are ineffective.

Cytadren

Cytadren, or aminoglutethimide, is primarily used to treat Cushing’s syndrome and hormone-dependent cancers like breast and prostate cancer. It works by inhibiting aromatase and blocking cholesterol conversion, reducing adrenal steroids production. Despite its effectiveness, Cytadren can cause side effects such as dizziness and gastrointestinal issues, thereby requiring careful medical supervision. Initially developed in the 1960s, it has been largely replaced by newer therapies.

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