lipid metabolism

Fatty acid anabolism, also known as lipogenesis, is the metabolic process through which cells synthesize fatty acids from acetyl-CoA and malonyl-CoA precursors. This biosynthesis primarily occurs in liver and adipose tissues, facilitated by the fatty acid synthase complex. The process starts with acetyl-CoA carboxylase catalyzing the formation of malonyl-CoA, followed by a series of reactions that elongate the carbon chain by two carbons per cycle, producing saturated fatty acids. NADPH and ATP are required, highlighting its energy-dependent nature.